Congenital Heart Disease

Congenital heart disease research uses cardiovascular MRI and 4D flow visualization to study repaired and complex anatomy across pediatric and life-course imaging.

Overview

Congenital heart disease is a clinical application area for 4D flow MRI.

Flow visualizations highlight complex patterns in repaired or altered anatomy.

Cardiovascular MRI methods support pediatric and life-course questions.

congenital heart diseasepediatric imagingflow visualization

Research overview

Selected work

4D flow yields similar clinical results compared to 2D phase contrast for decision making regarding pulmonary valve replacement in repaired tetralogy of Fallot

Almgren-Bell A, Popescu A, Sodhi A, Markl M, Rigsby CK, Robinson JD. Pediatr Cardiol. 2026.

GRASP reconstruction amplified with view-sharing and KWIC filtering reduces underestimation of peak velocity in highly-accelerated real-time phase-contrast MRI: A preliminary evaluation in pediatric patients with congenital heart disease

Yang H, Hong K, Baraboo JJ, Fan L, Larsen A, Markl M, et al. Magn Reson Med. 2024.

Hemodynamic evaluation of the pulmonary arteries and aorta using 4D flow cardiac MRI in children and young adults with dextro-transposition of the great arteries after the arterial switch operation

Calderon K, Sodhi A, Johnson EMI, Markl M, Robinson JD, Rigsby CK. Pediatr Radiol. 2025.